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Dual-Core Implantable Fiber Optic Cannulae


  • Dual-Core Cannulae with 700 µm Core Spacing
  • Two Ø200 µm Core Fibers with 0.39 NA
  • Ø2.5 mm Stainless Steel Ferrule
  • Custom Versions Available

CFM32L10

L = 10 mm

CFM32L20

L = 20 mm

Ø2.5 mm

Fiber Features a Precision Flat-Cleaved End

Ø2.5 mm Stainless Steel Ferrule Features an Alignment Pin Hole and 700 µm Core Spacing

700 µm

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Fiber Optic Cannula and Interconnect
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Thorlabs' Implantable Dual-Core Fiber Optic Cannulae are Compatible with our ADAF1 Mating Sleeve and Dual-Core Optogenetics Patch Cables
Key Specifications
Ferrule Size Ø2.5 mm x 10 mm
Ferrule Material Stainless Steel
Mass Approx. 0.18 g (0.0004 lbs)
Fiber Length 10 or 20 mm
Fiber Length Tolerance ±0.250 mma
Fiber Termination Flat Cleave
  • This tolerance applies to both the total fiber length and fiber length difference between the two fibers.

Features

  • Dual-Core Fiber Optic Cannulae for Bilateral Stimulation or Silencing Optogenetics Applications
  • Scorable Stainless Steel Ferrule for Better Adhesion to Skull
  • Ø200 µm, 0.39 NA Fiber with 700 µm Core Spacing
  • 10 or 20 mm Fiber Lengths
  • Sold Individually; Volume Pricing is Available
    (Contact optogenetics@thorlabs.com)
  • Contact Tech Support for Custom Cleave Length, Fiber Diameter, or Core Spacing

The dual-core cannulae sold on this page are specifically designed to be used with our dual-core fiber optic patch cablesThorlabs' dual-core products allow high-intensity light from two different sources to be implanted within a specimen in close proximity (~1 mm), and are therefore ideal for applications such as bilateral stimulation or silencing. 

These cannulae feature a Ø2.5 mm stainless steel ferrule with two Ø200 µm, 0.39 NA multimode fibers spaced 700 µm apart. Versions with a 10 mm or 20 mm fiber length are available from stock; for custom lengths, please contact Tech Support. Unlike a cannula with a single fiber, a dual-core cannula allows two fibers to be surgically implanted in a single procedure using stereotactic guidance. The stainless steel ferrule is easy to score for better adherence when implanted and fixed with glue.

For ease of use and alignment, the stainless steel ferrule is equipped with a Ø0.03" (Ø0.8 mm) guide hole which holds a matching mating pin in our dual-core patch cables using either the ADAF1 Mating Sleeve or ADAF2 Interconnect. As seen in the animation to the right, the mating pin and guide hole ensure precise alignment of the two fiber cores. The ferrule is engraved with an alignment mark that corresponds to a matching engraving on our dual-core fiber patch cables (see the image to the right). For more details on the usage of the dual-core patch cable and cannula, please see the Usage Tips tab above.

Each cannula includes a protective cap that shields the ferrule end from dust and other hazards when not in use. Additional caps, such as the CAPF Plastic Caps, are sold separately. If the ferrule or fiber ends become dirty from use, we offer a selection of inspection tools and fiber optic cleaning products.

Optogenetics Product Family for In Vivo Applications

The image below illustrates an example dual-core optogenetics system. Thorlabs offers a wide variety of products designed to support in vivo optogenetics applications. Please visit the OG Selection Guide tab above to see a full listing of available products for different applications.

Related Optogenetics Products
Light Sources Patch Cables (Ø200 µm Core, 0.39 NA) Mating Cannulae (Ø200 µm Core, 0.39 NA) Accessories
Fiber-Coupled LEDs
MM Laser, 473 nm
Standard
Rotary Joint
Dual Core
Bifurcated Y-Cables
Interconnects
Mating Sleeves
Standard
Dual Core
Diffuser Tip
Implant Guides
Cannula Holders

This tab contains instructions for assembling and disassembling a dual-core fiber optic patch cable and cannula. The animation to the right illustrates the assembly process using a dual-core patch cable, ADAF1 lightweight mating sleeve, and dual-core cannula. The ADAF2 Quick-Release Interconnect, which provides lower-force connections than the ADAF1 mating sleeve, can be found here.

Step 1: Ensure that the patch cable ferrule tip is clean and free of dust; we recommend our canned compressed air. Then, insert the patch cable ferrule approximately halfway into the Ø2.5 mm mating sleeve (Item # ADAF1). The ferrule should fit tightly within the mating sleeve.

Step 2: Similarly ensure that the ferrule tip of the cannula is clean and free of dust. Then, insert the cannula ferrule into the mating sleeve from the other side. If the two ferrules are properly aligned, the engraved markings on each ferrule should be aligned; if not, rotate the cannula until the engravings align. 

Step 3: Once aligned, gently press the two ferrules together until contact is achieved. Do not try to force the two ferrules together; if the alignment pin is misaligned, this may damage the ferrule.

For best results when disassembling, hold the patch cable near the jacket/ferrule interface and gently pull the ferrule from the ADAF1 mating sleeve. 


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Optogenetics Selection Guide

Thorlabs offers a wide range of optogenetics components; the compatibility of these products in select standard configurations is discussed in detail here. Please contact Technical Support for assistance with items outside the scope of this guide, including custom fiber components for optogenetics.

 

Single-Site Stimulation

One Light Source to One Cannula Implant

The most straightforward method for in vivo light stimulation of a specimen is to use a single fiber optic with a single LED light source. The single wavelength LED is powered by an LED driver, and then the illumination output is fiber-coupled into a patch cable, which connects to the implanted cannula. See the graphics and expandable compatibility tables below for the necessary patch cables and cannulae to create this setup. To choose the appropriate LED and driver, see below or the full web presentation.

Click on Each Component for More Information

LED DriverLED DriverFiber-Coupled LEDFiber-Coupled LEDSMA to Ferrule Patch Cable with Optional Rotary JointSMA to Ferrule Patch Cable with Optional Rotary JointADAF2 InterconnectADAF2 InterconnectFiber Optic CannulaFiber Optic Cannula



 

Bilateral Stimulation

The ability to accurately and simultaneously direct light to multiple locations within a specimen is desired for many types of optogenetics experiments. For example, bilateral stimulation techniques typically target neurons in two spatially separated regions in order to induce a desired behavior. In more complex experiments involving the simultaneous inhibition and stimulation of neurons, delivering light of two different monochromatic wavelengths within close proximity enables the user to perform these experiments without implanting multiple cannulae, which can increase stress on the specimen.

Bilateral stimulation can be achieved with several different configurations depending on the application requirements. The sections below illustrate examples of different configurations using Thorlabs' optogenetics products.


Option 1: One Light Source to Two Cannula Implants Using Rotary Joint Splitter

Thorlabs' RJ2 1x2 Rotary Joint Splitter is designed for optogenetics applications and is used to split light from a single input evenly between two outputs. The rotary joint interface allows connected patch cables to freely rotate, reducing the risk of fiber damage caused by a moving specimen. See the graphic and compatibility table below for the necessary cables and cannulae to create this setup. For LEDs and drivers, see below or the full web presentation.

LED DriverFiber-Coupled LEDHybrid Patch Cable1x2 Rotary Joint SplitterOG Patch CableOG Patch CableADAF2 InterconnectADAF2 InterconnectFiber Optic CannulaFiber Optic CannulaFiber Optic Cannula

Option 2: One or Two Light Sources to Two Cannula Implants

If the intent is for one LED source to connect to two cannulae for simultaneous light modulation, then a bifurcated fiber bundle can be used to split the light from the LED into each respective cannula. For dual wavelength stimulation (mixing two wavelengths in a single cannula) or a more controlled split ratio between cannula, one can use a multimode coupler to connect one or two LEDs to the cannulae. If one cable end is left unused, the spare coupler cable end may be terminated by a light trap. See the graphic and compatibility table below for the necessary cables and cannulae to create this setup. For LEDs and drivers, see below or the full web presentation.

Click on Each Component Below for More Information

LED DriverLED DriverFiber-Coupled LEDFiber-Coupled LEDPatch CabletextY-CableMating SleeveMating SleeveMating SleeveMating SleeveFiber Optic CannulaFiber Optic CannulaFiber Optic CannulaFiber Optic Cannula

LED Driver2nd LED DriverLED Driver textFiber-Coupled LED2nd Fiber-Coupled LEDFiber-Coupled LED textMultimode CouplerMultimode Coupler TextADAF2 InterconnectADAF2 Interconnect TextADAF2 InterconnectADAF2 Interconnect TextFiber Optic CannulaFiber Optic CannulaFiber Optic CannulaFiber Optic Cannula


 

Two Light Sources into One Dual-Core Cannula Implant

For bilateral stimulation applications where the two cannulas need to be placed in close proximity (within ~1 mm), Thorlabs offers dual-core patch cables and cannulae that are designed for this specific application. Each core is driven by a separate light source, enabling users to stimulate and/or supress nerve cells in the same region of the specimen. See the graphic and compatibility table below for the necessary cables and cannulae to create this setup. For LEDs and drivers, see below or the full web presentation.

LED Driver2nd LED DriverLED Driver TextFiber-Coupled LED2nd Fiber-Coupled LEDFiber-Coupled LEDsDual-Core Patch CableDual-Core Patch CableADAF2 InterconnectADAF2 InterconnectFiber Optic CannulaFiber Optic Cannula

Click on Each Component for More Information

Part Selection Table (Click Links for Item Description Popup)
Common Fiber Properties
Core Diameter 200 µm
Wavelength Range 400 - 2200 nm
NA 0.39
Fiber Type FT200EMT
Ferrule Stylea FC (Ø2.5 mm)
Dual-Core Patch Cable FC/PC Input BFY32FL1
SMA905 Input BFY32SL1
Compatible Mating Sleeve/Interconnect ADAF1
ADAF2
Dual-Core Fiber Optic Cannulaec Stainless Steel CFM32L10
CFM32L20
  • FC components have a Ø2.5 mm ferrule end.
  • Patch cables for dual light source to single implant applications are highlighted in green above. Choose a patch cable with an input that matches your light source.
  • Available cannulae are highlighted in orange of the table above. Cannule within the same column are interchangeable.

 

Popular Fiber-Coupled LEDs for Optogenetics
Item # M470F3 M590F2
Center Wavelength 470 nm 590 nm
Bandwidth (FWHM) 20 nm 15 nm
Typical Output Spectrum
(Click to Enlarge)
M470 Icon M470 Icon
Ø200 µm Core Fiber Output (Typ.)a
7.0 mW 0.68 mW
Ø400 µm Core Fiber Output (Typ.)b
21.8 mW 2.73 mW
CW Drive Current (Max) 1.0 A 1.0 A
LED Forward Voltage 3.1 V 2.8 V
Typical Lifetime >50,000 Hours >50,000 Hours
  • Tested using MM Fiber with Ø200 µm core, 0.22 NA (Item # FG200UCC).
  • Tested using MM Fiber with Ø400 µm core, 0.39 NA (Item # FT400EMT).

Illumination

Fiber-Coupled LEDs and Drivers

Our fiber-coupled LEDs are ideal light sources for optogenetics applications. They feature a variety of wavelength choices and a convenient interconnection to optogenetics patch cables. Thorlabs offers fiber-coupled LEDs with nominal wavelengths ranging from 280 nm to 1050 nm. See the table to the right for the LEDs with the most popular wavelengths for optogenetics. A table of compatible LED drivers can be viewed by clicking below.

Implantable Dual-Core Fiber Optic Cannulae with Ø2.5 mm Stainless Steel Ferrules

Image Ferrule Type Fiber Type Fiber Core
Diameter
Fiber Outer
Diameter
Core Spacing NA Wavelength Range Compatible Patch Cables
Cannulae with Ø2.5 mm Stainless Steel Ferrule and Ø200 µm Fiber Ø2.5 mm x 10 mm, Stainless FT200EMT 200 ± 5 µm 225 ± 5 µm 700 µm 0.39 ± 0.02 400 - 2200 nm BFY32 Dual-Core Patch Cables
Based on your currency / country selection, your order will ship from Newton, New Jersey  
+1 Qty Docs Part Number - Universal Price Available
CFM32L10 Support Documentation
CFM32L10Dual-Core Fiber Optic Cannula, Ø2.5 mm SS Ferrule, Ø200 µm Core, 700 µm Core Spacing, 0.39 NA, L=10 mm
$96.66
Today
CFM32L20 Support Documentation
CFM32L20Dual-Core Fiber Optic Cannula, Ø2.5 mm SS Ferrule, Ø200 µm Core, 700 µm Core Spacing, 0.39 NA, L=20 mm
$96.66
Today

Ø200 µm Core, 0.39 NA Dual-Core Patch Cables

These dual-core patch cables are designed to be used with the dual-core cannula sold above. They are connected to cannulae using mating sleeves or the quick release interconnect.

Item # Fiber
Type
Wavelength
Range
Core
Diameter

Core Spacing
NA Cable
Mass
Ferrule
Diameter
Ferrule
Material
Connectors Compatible
Cannulae
Operating
Temperature
BFY32FL1 FT200EMT
400 - 2200 nm 200 µm ± 5 µm 700 µm 0.39 118 g 2.5 mm Stainless Steel Two FC/PC to Ferrule CFM32 Dual-Core Cannulae -50 to 60 °C
BFY32SL1 Two SMA905 to Ferrule
Based on your currency / country selection, your order will ship from Newton, New Jersey  
+1 Qty Docs Part Number - Universal Price Available
BFY32FL1 Support Documentation
BFY32FL1Dual Ø200 µm Core, 700 µm Core Spacing, 0.39 NA, Patch Cable, FC/PC to Ø2.5 mm SS Ferrule, 1 m Long
$274.70
Today
BFY32SL1 Support Documentation
BFY32SL1Dual Ø200 µm Core, 700 µm Core Spacing, 0.39 NA, Patch Cable, SMA905 to Ø2.5 mm SS Ferrule, 1 m Long
$274.70
Today
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