Imaging Laser-Scanning Cytometry (LCS) combines the advantages of flow and image cytometry into a single system that provides unparalleled flexibility and power for rapid measurements of biochemical constituents or evaluating cell morphologies. Our series of LSC instruments are non-confocal systems that utilize laser-spot scanning illumination. The detection system, which combines PMTs for fluorescence detection and photodiodes for absorbance and scatter detection, offers excellent quantitative cytometric performance and imaging capabilities. The powerful and adaptable software provides full statistical analysis and composite imaging. Numerical data are displayed as traditional cytometric histograms or bivariate scattergram plots and can be related in a variety of ways to the image data from which they are derived.