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Art Conservation
Art Conservation
 
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Retina Imaging
 
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Drug Coating
 
Polarization Sensitive OCT
Polarization Sensitive OCT
 
AO enhanced OCT
AO enhanced OCT
 
Cochlear Implantation
Cochlear Implantation
 
Doppler OCT
Doppler OCT
 
Mouse Lung
Mouse Lung
Endoscopic Imaging
Endoscopic Imaging
 
Functional Imaging
Functional Imaging
 
Developmental Biology
Developmental Biology
 
3D Imaging
3D Imaging
 
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Peer Reviewed Papers
Developmental Biology

Optical Coherence Tomography (OCT) is a noninvasive imaging technique.  Given its imaging field of view of 1-10 mm, and imaging resolution of 2-20 um, OCT has been used extensively in developmental biology research to study the embryological development of various organs and systems. On this page we show real-time in vivo cross-sectional imaging of an African Frog (Xenopus laevis) during its tadpole stage.

Figure 1. African frog tadpole.

The tadpole was optically scanned using the Thorlabs OCM1300SS OCT microscope system. Each individual image is 6 mm x 8 mm. The complete data set contains 640 x 640 x 512 pixels and is acquired in about 30 seconds. Optical scans were taken from the posterior to the anterior of the tadpole in 100 µm incremental steps, as shown in Figure 2. The internal organ structure of the tadpole can be clearly visualized.

Figure 2. 3D optical sectioning of the African frog tadpole.

Product Links
 
Swept Source OCT Microscope System
Swept Source OCT Microscope System
 
Spectral Radar OCT Imaging System
Spectral Radar OCT Imaging System
 
Rapidly Swept Tunable Laser
Rapidly Swept Tunable Laser
 
 

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